Tuesday, February 15, 2011

Grades 9-12: Genetically Profiling Cancer


Content Provider COSI Columbus
Contact Information ElectronicEducation
electroniceducation@mail.cosi.org
333 West Broad Street
Columbus, OH 43215
United States
Phone: (614) 228-2674 ext. 0
Fax: (614) 228-6363
Program Type Individual Program
Program Rating This program has not yet been evaluated.
Target Audience Education: Grade(s): 9, 10, 11, 12, Public Library: Library Patrons
Maximum Number of Participants No Maximum
Minimum Number of Participants No Minimum
Primary Disciplines Career Education, Mathematics, Problem Solving, Sciences, Technology/Information Science
Program Description Dr. Jeff Palatini, Director of the Microarray Shared Resource (MASR) at the Comprehensive Cancer Center of The Ohio State University Medical Center (OSUMC), will discuss his work profiling genetic expression in cancer. By measuring the amount of RNA in tumor and normal cells, Dr. Palatini profiles which genes are more or less active in each. These profile comparisons implicate the role of certain genes for tumor activity in cancer cells and tumor suppression in normal cells. These genes can serve as potential targets for therapeutic intervention in cancer and other diseases. Genomics techniques can also monitor the efficacy of new drugs and therapies on cells before clinical trials in animals and humans begin.

Dr. Palatini has worked in the MASR Laboratory at OSUMC since its inception in 1997. The MASR Laboratory is a pioneer in the field of microarrays and next-generation sequencing. It was one of the first academic institutions to employ this technology. Dr. Palatini’s educational background is in microbiology and molecular genetics at OSU, as well as Pharmacology and Oncology at the University of Ferrara, in Italy. His work is focused primarily in molecular biology and genomics.

Students should have prior understanding of: basic cell processes such as DNA replication, the role of RNA in protein synthesis and basic familiarity with the structure of DNA
Program Format - Introduction of the Expert
- Presentation by the Expert
- Students share answers to challenge questions presented by the Expert
- Q&A with the Expert, in a round-robin fashion through all the schools connected
Objectives By participating in this program, students will:
- be exposed to science and technology applications in the real world
- face a challenge that scientists have
- explore various career paths in science and technology
- learn what they want to know about science and technology fields by directing questions at experts
National Standards to which this program aligns Specifics vary according to program.

Science content standards for grades 5-8:
A. Understandings about scientific inquiry
E. Understandings about science and technology
F. Science and technology in society
G. Science as a human endeavor, and the nature of science.

Science content standards for grades 9-12:
A. Understandings about scientific inquiry
E. Understandings about science and technology
F. Science and technology in local, national, and global challenges
G. Science as a human endeavor and the nature of scientific knowledge
Program Length 60 minutes
Dates/Times

Program DateProgram TimeNetwork TimeRegistration Deadline
All times below are displayed in Eastern Daylight Time, as specified in your profile.
4/20/20111:00 PM - 2:00 PM12:30 PM - 2:15 PM04/11/2011

Connection Type(s) Available and Program Fees Interactive Cost: $165.00
Cancellation Policy We ask that anyone making a reservation please check school calendars for holidays, professional development days and testing dates. We also ask that the person making the reservation please coordinate with teachers, technical coordinators, bridges and other interested parties prior to submitting the request. COSI will retain a $25 processing fee for ALL reservations and test connections: the processing fee and test connection are included in the price of the program. If you need to cancel a reservation, you must reschedule your program two weeks prior to the show. COSI will reschedule your program or test connection one time before an additional $25 rescheduling fee is added to the price. This $25 rescheduling fee applies to both program and test connections and will be added every time a schedule change is made beyond the first reschedule. COSI understands the occasional need to reschedule programs due to changing schedules, inclement weather or technical difficulties. However, COSI begins to commit time and resources to a program the moment a reservation is received.

COSI strongly recommends performing a test connection at least 2 days prior to the event. The school has the right to cancel any program the day of the test if a successful connection cannot be made and COSI will refund all but the $25 processing fee. If a school declines the test connection, or reschedules the program or test connection within the two-week period, COSI reserves the right to charge the full dollar amount for the program.
Is recording allowed? No
The Provider broadcasts over ISDN
Minimum Broadcast Speed: 128 K
Maximum Broadcast Speed: 512 K

IP
Minimum Technology Specifications for sites connecting to this provider We require schools connecting ISDN to dial into us. However, we can dial out to the ISDN schools and reverse line charges if special arrangements are made. We strongly recommend a connection speed of 384 or higher.

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